San Luis Rio Colorado, Mexico is a border city in Sonora known for its desert landscapes, agriculture, and proximity to the Colorado River and the US border. Visit the waterfront at the Colorado River delta, explore local markets and regional Sonoran cuisine, and drive to nearby El Golfo de Santa Clara and Puerto Penasco for beaches and birdwatching. Explore our San Luis Rio Colorado travel guides for the best things to do and travel tips.
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